The creation of the fluffy started with resequencing pony DNA basically from the ground up, adding new gene sequences as needed to get desired trates. Many of these genes came from other animals but some were completely artificial; these genes becoming the bio-organic programming seen inf fluffies today.
Once the prototype Genome was complete, it was implanted into an enucleated horse ovum and then gestated in a domestic pig. It took several attempts to produce a viable organism, often requiring modifications and correction be made to the prototype genome, but after 47 trial a fully viable specimen was created. Several dozen more were created using pigs as gestational hosts but a breeding population was eventually created. This first generation was the Model I fluffies.
Six years, and further research later, the Model II fluffies were created and the Model I were mostly “retired” with small populations being retained for research purposes. The Model II’s were used as gestational hosts to produce research and breeding populations of specialty fluffy breeds; Sea Fluffies, Garden Fluffies, Hunting Friends, etc. This excludes Micro-Fluffies and Breezies which were gestated inside guinea pigs and hamsters respectively initially.
Three years later, the Model III fluffies were created which became the standard experiment and breeding fluffies for many years. It wasn’t until six years after this, when the Model IV’s were created using artificial wombs, when the practice of using actual fluffies to breed new product was ceased, at least by Hasbio and its subsidiaries. The artificial wombs themselves would eventually stop being used some fifteen years later with invention of Live Organic 3D Printing (or LO3P) and the Model V fluffies.
The bio-organic programming ( or B.O.P.) was a brand new form of genetic engineering born of separate, repurposed research to code and store information into DNA in a manner similar to how one would store data onto a flashdrive. These gene sequences would code for regional structures in the brain very similar to those that are responsible for instincts in natural animals. B.O.P combined with retro-viral re-sequencers eventually created the controversial “Gene-Skill-Share” phenomenon some 78 years later.